Evidence map›Paper›PMID 10357855›Full record

ReviewMicrobiology and molecular biology reviews : MMBR1999

Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae.

F Pâques, J E Haber

Open access · bronzeAbstract readComparative StudyReview
In one paragraph

Review in Microbiology and molecular biology reviews : MMBR, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1,091 papers.

0numbers the graph read from it
0cells of the map it votes in
1,091citing papers in PubMed
44.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1,091 citing papers in PubMed, 2,119 citations in OpenAlex.

  1. Detection of "hidden" mitotic crossovers by long-read DNA sequencing.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Article
  3. Meiosis-specific genes play roles in ploidy reduction inProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Expression of EndonucleaseCurrent issues in molecular biology · 2026
    Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Mitotic recombination events and single-base mutations induced by ultraviolet light in G1-arrested yeast cells.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  15. Article
  16. Article
  17. Review
  18. Meiosis-specific genes play roles in ploidy reduction inbioRxiv : the preprint server for biology · 2025
    Article
  19. Structural basis for Rad54- and Hed1-mediated regulation of Rad51 during the transition from mitotic to meiotic recombination.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  20. Article

1,031 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

F PâquesRosenstiel Center and Department of Biology, Brandeis University, Waltham, Massachusetts 02454-9110, USA.
J E Haber
Brandeis University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The budding yeast Saccharomyces cerevisiae has been the principal organism used in experiments to examine genetic recombination in eukaryotes. Studies over the past decade have shown that meiotic recombination and probably most mitotic recombination arise from the repair of double-strand breaks (DSBs). There are multiple pathways by which such DSBs can be repaired, including several homologous recombination pathways and still other nonhomologous mechanisms. Our understanding has also been greatly enriched by the characterization of many proteins involved in recombination and by insights that link aspects of DNA repair to chromosome replication. New molecular models of DSB-induced gene conversion are presented. This review encompasses these different aspects of DSB-induced recombination in Saccharomyces and attempts to relate genetic, molecular biological, and biochemical studies of the processes of DNA repair and recombination.

Indexed as

Saccharomyces cerevisiae ProteinsAdenosine TriphosphatasesAnimalsDeoxyribonucleases, Type II Site-SpecificDNA-Binding ProteinsDNA DamageDNA, FungalDNA HelicasesDNA RepairDNA Repair EnzymesDNA ReplicationFungal ProteinsHumansMeiosisRad52 DNA Repair and Recombination ProteinRec A RecombinasesAdenosine TriphosphatasesDeoxyribonucleases, Type II Site-SpecificDNA-Binding ProteinsDNA, FungalDNA HelicasesDNA Repair EnzymesFungal ProteinsRad52 DNA Repair and Recombination ProteinRAD52 protein, S cerevisiaeRAD54 protein, S cerevisiaeRAD55 protein, S cerevisiaeRAD57 protein, S cerevisiaeRec A RecombinasesSaccharomyces cerevisiae ProteinsSCEI protein, S cerevisiae

Identifiers

PMID10357855
PMCPMC98970
OpenAlexW2144550200

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.