ReviewMicrobiology and molecular biology reviews : MMBR1999
Bioenergetic aspects of halophilism.
Review in Microbiology and molecular biology reviews : MMBR, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 282 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
282 citing papers in PubMed, 1,083 citations in OpenAlex.
- Data-driven optimization of salt shock for high-efficiency ectoine production inSynthetic and systems biotechnology · 2027Article
- Microbial community structure and function and their linkages with methane production in sediments of thermokarst lakes on the Tibetan Plateau.Science China. Life sciences · 2026Article
- Limits of bacterial osmoadaptation during planktonic and biofilm growth: a step toward effective biofouling control.Applied and environmental microbiology · 2026Article
- Comparative metagenomic analysis of microbial communities: unravelling microbial communities from the great Rann of Kachchh and coastal saltpans, Gujarat, India.Extremophiles : life under extreme conditions · 2026Article
- Review
- The extreme halophilic archaeonJournal of bacteriology · 2026Article
- Halophilic bacteria and archaea in salinity-resilient agriculture: mechanisms and multi-omics perspectives.Archives of microbiology · 2026Review
- Phenotypic, Pot-Experimental, and Genomic Characterization ofMicroorganisms · 2026Article
- Acetoclastic versus hydrogenotrophic methanogenesis: defining how pH and alkalinity shape acetate metabolism in a haloalkaliphilic methanogenic community for biomethane production.Applied microbiology and biotechnology · 2026Article
- Genomes of NBMC genomics · 2026Article
- Stress-Induced Cross-Protection and Combined Stress Responses in Extremotolerant Black Yeasts.Journal of fungi (Basel, Switzerland) · 2026Article
- Exploring Ectoine Production From Methanol, Formate, and Electrochemically Produced Formate byEngineering in life sciences · 2026Article
- Biosynthesis and import of the cytoprotective extremolytes ectoine and hydroxyectoine in the phylumFrontiers in microbiology · 2026Article
- Metagenomics reveal unrestricted dispersal of extreme halophiles and higher connectivity among coastal vs. inland solar salterns and hypersaline lakes.ISME communications · 2026Article
- Decoding metabolic trade-offs inSynthetic and systems biotechnology · 2025Article
- Cell-supporting cytoskeletons and phagocytic acquisition of compatible solutes emerge as common strategies for high-salt adaptation in different ciliates.Science China. Life sciences · 2025Article
- Article
- Article
- Effects of matric vs osmotic potential changes onmSystems · 2025Article
- Deciphering factors influencing planktonic and sedimentary microbial assembly processes in Midwest salinity lakes.Applied microbiology and biotechnology · 2025Article
222 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Examination of microbial diversity in environments of increasing salt concentrations indicates that certain types of dissimilatory metabolism do not occur at the highest salinities. Examples are methanogenesis for H2 + CO2 or from acetate, dissimilatory sulfate reduction with oxidation of acetate, and autotrophic nitrification. Occurrence of the different metabolic types is correlated with the free-energy change associated with the dissimilatory reactions. Life at high salt concentrations is energetically expensive. Most bacteria and also the methanogenic Archaea produce high intracellular concentrations of organic osmotic solutes at a high energetic cost. All halophilic microorganisms expend large amounts of energy to maintain steep gradients of NA+ and K+ concentrations across their cytoplasmic membrane. The energetic cost of salt adaptation probably dictates what types of metabolism can support life at the highest salt concentrations. Use of KCl as an intracellular solute, while requiring far-reaching adaptations of the intracellular machinery, is energetically more favorable than production of organic-compatible solutes. This may explain why the anaerobic halophilic fermentative bacteria (order Haloanaerobiales) use this strategy and also why halophilic homoacetogenic bacteria that produce acetate from H2 + CO2 exist whereas methanogens that use the same substrates in a reaction with a similar free-energy yield do not.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.