Evidence map›Paper›PMID 1033797›Full record

ArticleClinical and experimental immunology1976

Acquisition of human blood group antigens by Schistosoma mansoni.

O L Goldring, J A Clegg, S R Smithers, R J Terry

Abstract read
In one paragraph

Article in Clinical and experimental immunology, 1976. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Association between ABO blood groups and COVID-19 infection, severity and demise: A systematic review and meta-analysis.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2020
    Pooled it
  2. Oxidative Stress and Cancer Risk in Schistosomiasis.Oxidative medicine and cellular longevity · 2024
    Review
  3. The Biological Significance of Trogocytosis.Results and problems in cell differentiation · 2024
    Article
  4. ABO Blood Groups Do Not PredictMicroorganisms · 2021
    Article
  5. Review
  6. Revisiting the Mechanisms of Immune Evasion Employed by Human Parasites.Frontiers in cellular and infection microbiology · 2021
    Review
  7. Article
  8. Review
  9. Systematic screening of 96Wellcome open research · 2019
    Article
  10. Review
  11. Article
  12. Article
  13. Immunology of human schistosomiasis.Parasite immunology · 2014
    Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

O L Goldring
J A Clegg
S R Smithers
R J Terry

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Juvenile forms of Schistosoma mansoni (schistosomula) have been cultured in human blood of various specificities and tested for the presence of blood group substances on their surfaces. The tests employed were survival following transfer into rhesus monkeys immunized against human blood substances, mixed agglutination reactions, and immunofluorescence. A, B, H AND Lewisb+ antigens were expressed at the surface when the parasites were cultured in blood of appropriate specificities. Rhesus, M N S, AND Duffy antigens could not be detected on the parasite surface following culture. The evidence suggests that the expressed blood group antigens are of host origin and are acquired by the parasite during culture, probably in the form of glycolipids or megaloglycolipids. It is likely that these substances are also acquired by parasites in the bloodstream of man. They may serve to mask surface parasite antigens, and so enable schistosomes to evade parasite-specific humoral or cellular immune responses.

Indexed as

Blood Group AntigensABO Blood-Group SystemAgglutination TestsAnimalsAntigensBinding SitesHumansImmunizationMacaca mulattaSchistosoma mansoniABO Blood-Group SystemAntigensBlood Group Antigens

Identifiers

PMID1033797
PMCPMC1540823

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.