ArticleThe Plant cell1999
Molecular markers and cell cycle inhibitors show the importance of cell cycle progression in nematode-induced galls and syncytia.
Article in The Plant cell, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
89 citing papers in PubMed, 216 citations in OpenAlex.
- Quantitative live-cell imaging of auxin and cytokinin signalling in developing feeding sites ofPlant signaling & behavior · 2026Article
- Resistance breaking Root-knot nematodes carry a fitness cost associated with defective feeding site development.PLoS pathogens · 2026Article
- A spatiotemporal atlas of giant-cell formation during Meloidogyne incognita infection in tomato roots.Molecular horticulture · 2026Article
- Root-knot-nematode-derived mimics of RGF peptides hijack host signalling to orchestrate feeding site formation.Nature plants · 2026Article
- A multi-omics approach reveals that the plant-parasitic nematodeParasitology · 2026Article
- The Nuclear Effector RIRG190 Interacts with SAS10 to Regulate Arbuscular Mycorrhizal Symbiosis.International journal of molecular sciences · 2025Article
- Single-nucleus RNA-sequencing reveals the cellular programs driving nematode-induced giant cell formation in tomato.Horticulture research · 2025Article
- Cellular plasticity and transcriptional reprogramming in plant-nematode interactions: insights into feeding site formation and plant defense.Crop health · 2025Review
- Article
- The potato RNA metabolism machinery is targeted by the cyst nematode effector RHA1B for successful parasitism.The Plant cell · 2024Article
- Local and systemic transcriptome and spliceome reprogramming induced by the root-knot nematodeHorticulture research · 2024Article
- Soybean MKK2 establishes intricate signalling pathways to regulate soybean response to cyst nematode infection.Molecular plant pathology · 2024Article
- Functional consequences of somatic polyploidy in development.Development (Cambridge, England) · 2024Review
- Functional studies of plant transcription factors and their relevance in the plant root-knot nematode interaction.Frontiers in plant science · 2024Review
- Galls induced by a root-knot nematode in Petroselinum crispum (Mill.): impacts on host development, histology, and cell wall dynamics.Protoplasma · 2023Article
- Characterization of Arbuscular Mycorrhizal Effector Proteins.International journal of molecular sciences · 2023Review
- The Minichromosome Maintenance Complex Component 2 (MjMCM2) of Meloidogyne javanica is a potential effector regulating the cell cycle in nematode-induced galls.Scientific reports · 2022Article
- Morphological characterization reveals new insights into giant cell development of Meloidogyne graminicola on rice.Planta · 2022Article
- Local auxin synthesis mediated by YUCCA4 induced during root-knot nematode infection positively regulates gall growth and nematode development.Frontiers in plant science · 2022Article
- The GpIA7 effector from the potato cyst nematode Globodera pallida targets potato EBP1 and interferes with the plant cell cycle.Journal of experimental botany · 2021Article
29 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Root knot and cyst nematodes induce large multinucleated cells, designated giant cells and syncytia, respectively, in plant roots. We have used molecular markers to study cell cycle progression in these specialized feeding cells. In situ hybridization with two cyclin-dependent kinases and two cyclins showed that these genes were induced very early in galls and syncytia and that the feeding cells progressed through the G2 phase. By using cell cycle blockers, DNA synthesis and progression through the G2 phase, or mitosis, were shown to be essential for gall and syncytium establishment. When mitosis was blocked, further gall development was arrested. This result demonstrates that cycles of endoreduplication or other methods of DNA amplification are insufficient to drive giant cell expansion. On the other hand, syncytium development was much less affected by a mitotic block; however, syncytium expansion was inhibited.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.