Evidence map›Paper›PMID 10322034›Full record

ArticleJournal of bacteriology1999

Bacteriocin release protein triggers dimerization of outer membrane phospholipase A in vivo.

N Dekker, J Tommassen, H M Verheij

Open access · bronzeAbstract read
In one paragraph

Article in Journal of bacteriology, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Colicins and Microcins Produced byInternational journal of environmental research and public health · 2022
    Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Colicin biology.Microbiology and molecular biology reviews : MMBR · 2007
    Review
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

N DekkerDepartment of Enzymology and Protein Engineering, Center for Biomembranes and Lipid Enzymology, Utrecht University, 3584 CH Utrecht, The Netherlands. n.dekker@chem.uu.nl
J Tommassen
H M Verheij
Institute of Molecular Life Sciences · HUUtrecht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacteriocin release protein is known to activate outer membrane phospholipase A (OMPLA), which results in the release of colicin from Escherichia coli. In vivo chemical cross-linking experiments revealed that the activation coincides with dimerization of OMPLA. Permeabilization of the cell envelope and dimerization were characterized by a lag time of 2 h.

Indexed as

LipoproteinsAlkaline PhosphataseBacterial Outer Membrane ProteinsBacterial ProteinsCell Membrane PermeabilityChloramphenicol O-AcetyltransferaseCross-Linking ReagentsCytosolDimerizationEnzyme ActivationEscherichia coliModels, BiologicalPeriplasmPhospholipases AProtein BindingTime FactorsAlkaline PhosphataseBacterial Outer Membrane ProteinsBacterial ProteinsCAL protein, Citrobacter freundiiChloramphenicol O-AcetyltransferaseCross-Linking ReagentsLipoproteinsPhospholipases A

Identifiers

PMID10322034
PMCPMC93788
OpenAlexW2134585889

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.