ArticleProceedings of the National Academy of Sciences of the United States of America1999
Exon repetition in mRNA.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 56 citations in OpenAlex.
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- Circular RNA circCCNT2 is upregulated in the anterior cingulate cortex of individuals with bipolar disorder.Translational psychiatry · 2021Article
- Circular RNAs in Hedgehog Signaling Activation and Hedgehog-Mediated Medulloblastoma Tumors.Cancers · 2021Article
- Review
- Detecting and characterizing circular RNAs.Nature biotechnology · 2014Article
- Barnacle: detecting and characterizing tandem duplications and fusions in transcriptome assemblies.BMC genomics · 2013Article
- Dissect: detection and characterization of novel structural alterations in transcribed sequences.Bioinformatics (Oxford, England) · 2012Article
- Post-transcriptional exon shuffling events in humans can be evolutionarily conserved and abundant.Genome research · 2011Article
- Trans-splicing in Higher Eukaryotes: Implications for Cancer Development?Frontiers in genetics · 2011Article
- Transcriptome-guided characterization of genomic rearrangements in a breast cancer cell line.Proceedings of the National Academy of Sciences of the United States of America · 2009Article
- Short homologous sequences are strongly associated with the generation of chimeric RNAs in eukaryotes.Journal of molecular evolution · 2009Article
- Controlled chaos of polymorphic mucins in a metazoan parasite (Schistosoma mansoni) interacting with its invertebrate host (Biomphalaria glabrata).PLoS neglected tropical diseases · 2008Article
- A genome-wide survey demonstrates widespread non-linear mRNA in expressed sequences from multiple species.Nucleic acids research · 2005Article
- Exon repetition: a major pathway for processing mRNA of some genes is allele-specific.Nucleic acids research · 2004Article
- Alternative trans-splicing of constant and variable exons of a Drosophila axon guidance gene, lola.Genes & development · 2003Article
- Molecular mechanisms governing Pcdh-gamma gene expression: evidence for a multiple promoter and cis-alternative splicing model.Genes & development · 2002Article
- The contribution of exon-skipping events on chromosome 22 to protein coding diversity.Genome research · 2001Article
- Localization of an exonic splicing enhancer responsible for mammalian natural trans-splicing.Nucleic acids research · 2001Article
- Article
- Evidence for the function of an exonic splicing enhancer after the first catalytic step of pre-mRNA splicing.Proceedings of the National Academy of Sciences of the United States of America · 1999Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
The production of different transcripts (transcript heterogeneity) is a feature of many genes that may result in phenotypic variation. Several mechanisms, that occur at both the DNA and RNA level have been shown to contribute to this transcript heterogeneity in mammals, all of which involve either the rearrangement of sequences within a genome or the use of alternative signals in linear, contiguous DNA or RNA. Here we describe tissue-specific repetition of selective exons in transcripts of a rat gene (SA) with a normal exon-intron organization. We conclude that nonlinear mRNA processing can generate tissue-specific transcripts.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.