Evidence map›Paper›PMID 10235603›Full record

ArticleDigestive diseases and sciences1999

Chronic intestinal pseudoobstruction syndrome: clinical analysis, outcome, and prognosis in 105 children. French-Speaking Group of Pediatric Gastroenterology.

C Faure, O Goulet, S Ategbo, A Breton, P Tounian, J L Ginies, B Roquelaure, C Despres, M Scaillon, C Maurage and 7 more

Registry-linked trialAbstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Digestive diseases and sciences, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03012594 (A Pilot Study to Evaluate Safety and Effectiveness of Lanreotide in the Treatment of Patients With Small Bowel Motility Disorders), which is not on this map. Cited by 32 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03012594 phase2completednot on this mapstarted 2017, after this paper: background citation

A Pilot Study to Evaluate Safety and Effectiveness of Lanreotide in the Treatment of Patients With Small Bowel Motility Disorders (SBMD): a Prospective, Non-randomized, Single-center Study of 20 Participants

TypeinterventionalSponsorNorthwell HealthRan2017 to 2019Enrolled12ConditionsGastrointestinal Motility Disorder, Intestinal DiseaseArmsLanreotide
3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review of nutrition management of pediatric intestinal pseudo-obstruction.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2026
    Review
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  6. Article
  7. Article
  8. Observational
  9. Observational
  10. Article
  11. Journal of neurogastroenterology and motility · 2022
    Article
  12. Review
  13. Article
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  15. Article
  16. Review
  17. Review
  18. Article
  19. Review
  20. Assessment and outcome of pediatric intestinal pseudo-obstruction: A tertiary-care-center experience from Turkey.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

C FaureService de Gastroentérologie Pédiatrique, Hôpital Robert Debré, Paris, France.
O Goulet
S Ategbo
A Breton
P Tounian
J L Ginies
B Roquelaure
C Despres
M Scaillon
C Maurage
I Paquot
M Hermier
S De Napoli
A Dabadie
F Huet
J J Baudon
M Larchet

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our aim was to collect a large number of cases to characterize clinical presentation, outcome, and prognosis of chronic intestinal pseusoobstruction in children. We conducted a retrospective multicenter study that included children treated for chronic intestinal pseusoobstruction defined as recurrent episodes of intestinal obstruction with no mechanical obstruction, excluding Hirschsprung's disease. In all, 105 children, 57 boys and 48 girls, were studied, including five familial forms. Prenatal diagnosis was made in 18 patients. Eighty patients were less than 12 months old at onset; the disease began at birth for 37 patients. The most frequent signs were abdominal distension, vomiting, and constipation. Megacystis was noted in myopathies (7 cases), neuropathies (10 cases) and unclassified forms (13 cases). For all but three cases (two patients with CMV infection, one with Munchhausen-by-proxy syndrome), the associated diseases and disorders could not account for chronic intestinal pseusoobstruction as a secondary disorder. At least one full-thickness biopsy from the digestive tract was studied for 99 patients. The diagnosis recorded was visceral neuropathy in 58 cases, visceral myopathy in 17 cases, and uncertain or normal biopsy results in 24 cases. Seventy-eight children were fed intravenously, and only 18 were able to be fed orally throughout their illness. Seventy-one patients underwent surgery during their illness, and 217 surgical procedures, a mean of 3 per patient, were performed. Ostomy was the most performed procedure. Follow-up continued in 89 patients for 3 months to 16 years (mean 85 months). Forty-two patients were still fed by parenteral (39 patients) or enteral nutrition (3 patients) at the time of the study. Eleven patients died between the age of 1 month and 14 years 7 months.

Indexed as

Age of OnsetChildChild, PreschoolChronic DiseaseFemaleHumansInfantInfant, NewbornIntestinal ObstructionMalePrognosisRetrospective StudiesSurvival AnalysisSyndromeTreatment Outcome

Identifiers

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.