ArticleImmunology1999
T-cell populations in the pig intestinal lamina propria: memory cells with unusual phenotypic characteristics.
Article in Immunology, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 40 citations in OpenAlex.
- A review of CD4Veterinary immunology and immunopathology · 2024Review
- Intraepithelial lymphocytes in the pig intestine: T cell and innate lymphoid cell contributions to intestinal barrier immunity.Frontiers in immunology · 2022Review
- Single-Blinded Study Highlighting the Differences between the Small Intestines of Neonatal and Weaned Piglets.Animals : an open access journal from MDPI · 2021Article
- The development and role of microbial-host interactions in gut mucosal immune development.Journal of animal science and biotechnology · 2017Review
- Rearing environment affects development of the immune system in neonates.Clinical and experimental immunology · 2010Article
- Article
- CD4+ T-cell responses and distribution at the colonic mucosa during Brachyspira hyodysenteriae-induced colitis in pigs.Immunology · 2005Article
- Professional and non-professional antigen-presenting cells in the porcine small intestine.Immunology · 2000Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We have previously presented evidence of a highly organized and compartmentalized structure of the small intestinal lamina propria of the pig. In this study, we conducted a detailed analysis of the T-cell populations found at this site, and compared these T cells with cell populations found in other tissue sites and the periphery. We showed that the CD4+ and CD8+ T-cell populations found in the pig gut are of memory phenotype, defined by CD45 isoform expression, but show few signs of recent activation. They show a high degree of phenotypic and therefore presumably functional homogeneity. Both CD4- and CD8-positive cells show strong parallels in the patterns of surface molecule expression, suggesting similar pressures on differentiation. The unique combination of surface molecules found on lamina propria T cells is found only infrequently on cells in other lymphoid sites.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.