ArticleGenetics1999
Recombination and selection at Brassica self-incompatibility loci.
Article in Genetics, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed.
- Article
- Inbreeding depression in self-incompatible North-American Arabidopsis lyrata: disentangling genomic and S-locus-specific genetic load.Heredity · 2013Article
- Amino acid repeats cause extraordinary coding sequence variation in the social amoeba Dictyostelium discoideum.PloS one · 2012Article
- Sporophytic self-incompatibility genes and mating system variation in Arabis alpina.Annals of botany · 2011Article
- Creation and maintenance of variation in allorecognition Loci: molecular analysis in various model systems.Frontiers in immunology · 2011Article
- Antagonism between local dispersal and self-incompatibility systems in a continuous plant population.Molecular ecology · 2009Article
- In vivo detection of residues required for ligand-selective activation of the S-locus receptor in Arabidopsis.Current biology : CB · 2009Article
- Article
- Molecular population genetics of the SRK and SCR self-incompatibility genes in the wild plant species Brassica cretica (Brassicaceae).Genetics · 2009Article
- Detecting groups of coevolving positions in a molecule: a clustering approach.BMC evolutionary biology · 2007Article
- Effects of recombination on hitchhiking diversity in the Brassica self-incompatibility locus complex.Genetics · 2007Article
- Article
- Comparison of the genome structure of the self-incompatibility (S) locus in interspecific pairs of S haplotypes.Genetics · 2006Article
- Phenotypic variation and natural selection at catsup, a pleiotropic quantitative trait gene in Drosophila.Current biology : CB · 2006Article
- Duplication, balancing selection and trans-species evolution explain the high levels of polymorphism of the DQA MHC class II gene in voles (Arvicolinae).Immunogenetics · 2006Article
- Article
- Balancing selection in the wild: testing population genetics theory of self-incompatibility in the rare species Brassica insularis.Genetics · 2005Article
- Evidence for recombination in scorpion mitochondrial DNA (Scorpiones: Buthidae).Proceedings. Biological sciences · 2005Article
- Diversity and linkage of genes in the self-incompatibility gene family in Arabidopsis lyrata.Genetics · 2003Article
- Coevolution of the S-locus genes SRK, SLG and SP11/SCR in Brassica oleracea and B. rapa.Genetics · 2002Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In Brassica species, self-incompatibility is controlled genetically by haplotypes involving two known genes, SLG and SRK, and possibly an as yet unknown gene controlling pollen incompatibility types. Alleles at the incompatibility loci are maintained by frequency-dependent selection, and diversity at SLG and SRK appears to be very ancient, with high diversity at silent and replacement sites, particularly in certain "hypervariable" portions of the genes. It is important to test whether recombination occurs in these genes before inferences about function of different parts of the genes can be made from patterns of diversity within their sequences. In addition, it has been suggested that, to maintain the relationship between alleles within a given S-haplotype, recombination is suppressed in the S-locus region. The high diversity makes many population genetic measures of recombination inapplicable. We have analyzed linkage disequilibrium within the SLG gene of two Brassica species, using published coding sequences. The results suggest that intragenic recombination has occurred in the evolutionary history of these alleles. This is supported by patterns of synonymous nucleotide diversity within both the SLG and SRK genes, and between domains of the SRK gene. Finally, clusters of linkage disequilibrium within the SLG gene suggest that hypervariable regions are under balancing selection, and are not merely regions of relaxed selective constraint.
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