ArticleAJNR. American journal of neuroradiology1999
Segmental spinal dysgenesis: neuroradiologic findings with clinical and embryologic correlation.
Article in AJNR. American journal of neuroradiology, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
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Who cites it
44 citing papers in PubMed, 114 citations in OpenAlex.
- Fetal imaging approach to spinal dysraphism diagnosis.Pediatric radiology · 2026Review
- Growth-Based Decision-Making in Congenital Scoliosis with Multiple Vertebral Anomalies.Journal of clinical medicine · 2026Review
- Case Report: Segmental spinal cord hypoplasia in a Labrador Retriever puppy.Frontiers in veterinary science · 2026Article
- A rare presentation of segmental spinal dysgenesis: Clinical and radiological findings.Radiology case reports · 2024Article
- Clinical and radiological evaluation of caudal regression syndrome.Pediatric radiology · 2024Review
- International Consensus Statement on the Radiological Evaluation of Dysraphic Malformations of the Spine and Spinal Cord.AJNR. American journal of neuroradiology · 2024Review
- Sacral agenesis without maternal diabetes: a case report.Annals of medicine and surgery (2012) · 2023Article
- Severe type of segmental spinal dysgenesis with complete disconnection of the spinal cord and vertebra associated with open neural tube defect.Surgical neurology international · 2023Article
- Junctional Neurulation : A Junction between Primary and Secondary Neural Tubes.Journal of Korean Neurosurgical Society · 2021Article
- Surgical treatment of segmental spinal dysgenesis: a report of 19 cases.Spine deformity · 2021Article
- Unveiling the tale of the tail: an illustration of spinal dysraphisms.Neurosurgical review · 2021Review
- Caudal regression syndrome and a pelvic kidney: case report.Anatomy & cell biology · 2020Article
- Segmental spinal dysgenesis with open spinal dysraphism and Chiari II features, case report.Radiology case reports · 2020Article
- Perosomus elumbis in a stillborn rhesus macaque (Macaca mulatta): A case report.Journal of medical primatology · 2020Article
- Do junctional neural tube defect and segmental spinal dysgenesis have the same pathoembryological background?Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2020Article
- Segmental Spinal Dysgenesis.Ochsner journal · 2020Article
- Segmental Spinal Dysgenesis-"Redefined".Asian spine journal · 2019Article
- Caudal Regression Syndrome with Pressure Ulcers of the Foot: A Case Report.Journal of clinical and diagnostic research : JCDR · 2017Article
- Imaging spectrum of spinal dysraphism on magnetic resonance: A pictorial review.World journal of radiology · 2017Review
- Segmental spinal dysgenesis with caudal agenesis in a Holstein calf.The Journal of veterinary medical science · 2017Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeSegmental spinal dysgenesis (SSD) is a rare congenital abnormality in which a segment of the spine and spinal cord fails to develop properly. Our goal was to investigate the neuroradiologic features of this condition in order to correlate our findings with the degree of residual spinal cord function, and to provide insight into the embryologic origin of this disorder. We also aimed to clarify the relationship between SSD and other entities, such as multiple vertebral segmentation defects, congenital vertebral displacement, and caudal regression syndrome (CRS).
methodsThe records of patients treated at our institutions for congenital spinal anomalies were reviewed, and 10 cases were found to satisfy the inclusion criteria for SSD. Plain radiographs were available for review in all cases. MR imaging was performed in eight patients, one of whom also underwent conventional myelography. Two other patients underwent only conventional myelography.
resultsSegmental vertebral anomalies involved the thoracolumbar, lumbar, or lumbosacral spine. The spinal cord at the level of the abnormality was thinned or even indiscernible, and a bulky, low-lying cord segment was present caudad to the focal abnormality in most cases. Closed spinal dysraphisms were associated in five cases, and partial sacrococcygeal agenesis in three. Renal anomalies were detected in four cases, and dextrocardia in one; all patients had a neurogenic bladder.
conclusionSSD is an autonomous entity with characteristic clinical and neuroradiologic features; however, SSD and CRS probably represent two faces of a single spectrum of segmental malformations of the spine and spinal cord. The neuroradiologic picture depends on the severity of the malformation and on its segmental level along the longitudinal embryonic axis. The severity of the morphologic derangement correlates with residual spinal cord function and with severity of the clinical deficit.
Indexed as
Identifiers
10219410PMC7056058W2162505697What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.