ReviewChest1999
Mycoplasma pneumoniae-associated bronchiolitis causing severe restrictive lung disease in adults: report of three cases and literature review.
Review in Chest, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 71 citations in OpenAlex.
- Article
- LncNFYC-AS1 ameliorates Mycoplasma pneumoniae pneumonia via regulating miR-1323.BMC pulmonary medicine · 2025Article
- The Immune Modulatory Role of Surfactants inJournal of inflammation research · 2025Review
- Cryptogenic Organizing Pneumonia Secondary to Mycoplasma pneumoniae Infection: A Case Report.Cureus · 2021Article
- Mechanism of azithromycin in airway diseases.The Journal of international medical research · 2020Review
- Clinicoradiologic features ofPediatric investigation · 2018Article
- Mycoplasma pneumoniae-Associated Bronchiolitis Obliterans Following Acute Bronchiolitis.Scientific reports · 2017Article
- Review
- Correlation between Radiological and Pathological Findings in Patients with Mycoplasma pneumoniae Pneumonia.Frontiers in microbiology · 2016Review
- Novel aspects on the pathogenesis of Mycoplasma pneumoniae pneumonia and therapeutic implications.Frontiers in microbiology · 2014Review
- Effect of puerarin on the release of interleukin-8 in co-culture of human bronchial epithelial cells and neutrophils.Chinese journal of integrative medicine · 2012Article
- Pulmonary surfactant phosphatidylglycerol inhibits Mycoplasma pneumoniae-stimulated eicosanoid production from human and mouse macrophages.The Journal of biological chemistry · 2011Article
- Identification of a mechanism for lung inflammation caused by Mycoplasma pneumoniae using a novel mouse model.Results in immunology · 2011Article
- Organizing pneumonia associated with Mycoplasma pneumoniae infection.Japanese journal of radiology · 2010Article
- Induction of IL-8 by Mycoplasma pneumoniae membrane in BEAS-2B cells.American journal of physiology. Lung cellular and molecular physiology · 2008Article
- Fatal Mycoplasma pneumoniae pneumonia in a previously healthy 18-year-old girl.Wiener klinische Wochenschrift · 2007Article
- Bronchiolitis obliterans.Clinical reviews in allergy & immunology · 2003Review
- Effects of respiratory Mycoplasma pneumoniae infection on allergen-induced bronchial hyperresponsiveness and lung inflammation in mice.Infection and immunity · 2003Article
- Wheeze and Mycoplasma pneumoniae.Journal of the Royal Society of Medicine · 2002Article
- Significant role of interleukin-8 in pathogenesis of pulmonary disease due to Mycoplasma pneumoniae infection.Clinical and diagnostic laboratory immunology · 2001Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
STUDY
objectivesTo characterize adult Mycoplasma pneumoniae-induced bronchiolitis requiring hospitalization.
designWe encountered an adult patient with severe bronchiolitis in the absence of pneumonia due to M. pneumoniae. To determine the relative frequency of such a condition, we retrospectively reviewed the medical records of adults over a 4-year period with a hospital discharge diagnosis of "bronchiolitis" from a university hospital.
settingUniversity Hospital of the University of Colorado Health Sciences Center, Denver, CO. STUDY SUBJECTS: From 1994 to 1998, 10 adult inpatients were identified with a diagnosis of bronchiolitis. There were two with respiratory bronchiolitis, one with panbronchiolitis, one patient with bronchiolitis obliterans organizing pneumonia (BOOP), and six with acute inflammatory bronchiolitis. Including the initial patient, three had a definitive clinical diagnosis of Mycoplasma-associated bronchiolitis.
resultsThe three adult patients with bronchiolitis due to M. pneumoniae are unusual because they occurred in the absence of radiographic features of a lobar or patchy alveolar pneumonia. Hospital admission was occasioned by the severity of symptoms and gas exchange abnormalities. One patient had bronchiolitis as well as organizing pneumonia (BOOP) that responded favorably to corticosteroid treatment. The other two had high-resolution CT findings diagnostic of an acute inflammatory bronchiolitis. One of the patients with inflammatory bronchiolitis had an unusual pattern of marked ventilation and perfusion defects localized predominantly to the left lung. All three had restrictive ventilatory impairment on physiologic testing.
conclusionsIn adults, Mycoplasma-associated bronchiolitis without pneumonia is rarely reported, but in hospitalized patients, it may be more common than expected and may be associated with severe physiologic disturbances.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.