ArticleProceedings of the National Academy of Sciences of the United States of America1999
The membrane-attached electron carrier cytochrome cy from Rhodobacter sphaeroides is functional in respiratory but not in photosynthetic electron transfer.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 45 citations in OpenAlex.
- Tellurite and Selenite: how can these two oxyanions be chemically different yet so similar in the way they are transformed to their metal forms by bacteria?Biological research · 2022Review
- Catalytic Reactions and Energy Conservation in the CytochromeChemical reviews · 2021Review
- Probing the local lipid environment of the Rhodobacter sphaeroides cytochrome bcBiochimica et biophysica acta. Bioenergetics · 2018Article
- Article
- Missense mutations in cytochrome c maturation genes provide new insights into Rhodobacter capsulatus cbb3-type cytochrome c oxidase biogenesis.Journal of bacteriology · 2013Article
- Application of universal stress proteins in probing the dynamics of potent degraders in complex terephthalate metagenome.BioMed research international · 2013Article
- The cytochrome c maturation components CcmF, CcmH, and CcmI form a membrane-integral multisubunit heme ligation complex.The Journal of biological chemistry · 2008Article
- Demonstration of short-lived complexes of cytochrome c with cytochrome bc1 by EPR spectroscopy: implications for the mechanism of interprotein electron transfer.The Journal of biological chemistry · 2008Article
- Stability of the cbb3-type cytochrome oxidase requires specific CcoQ-CcoP interactions.Journal of bacteriology · 2008Article
- Soluble variants of Rhodobacter capsulatus membrane-anchored cytochrome cy are efficient photosynthetic electron carriers.The Journal of biological chemistry · 2008Article
- Cytochrome bc1-cy fusion complexes reveal the distance constraints for functional electron transfer between photosynthesis components.The Journal of biological chemistry · 2008Article
- Transcriptome dynamics during the transition from anaerobic photosynthesis to aerobic respiration in Rhodobacter sphaeroides 2.4.1.Journal of bacteriology · 2008Article
- Membrane-spanning and periplasmic segments of CcmI have distinct functions during cytochrome c Biogenesis in Rhodobacter capsulatus.Journal of bacteriology · 2007Article
- Photosynthesis research in Italy: a review.Photosynthesis research · 2006Review
- Uncovering the molecular mode of action of the antimalarial drug atovaquone using a bacterial system.The Journal of biological chemistry · 2005Article
- Membrane-anchored cytochrome c as an electron carrier in photosynthesis and respiration: past, present and future of an unexpected discovery.Photosynthesis research · 2003Article
- Photosynthesis genes and their expression in Rhodobacter sphaeroides 2.4.1: a tribute to my students and associates.Photosynthesis research · 2002Article
- Mobile cytochrome c2 and membrane-anchored cytochrome cy are both efficient electron donors to the cbb3- and aa3-type cytochrome c oxidases during respiratory growth of Rhodobacter sphaeroides.Journal of bacteriology · 2001Article
- Redox signaling: globalization of gene expression.The EMBO journal · 2000Article
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
Rhodobacter species are useful model organisms for studying the structure and function of c type cytochromes (Cyt c), which are ubiquitous electron carriers with essential functions in cellular energy and signal transduction. Among these species, Rhodobacter capsulatus has a periplasmic Cyt c2Rc and a membrane-bound bipartite Cyt cyRc. These electron carriers participate in both respiratory and photosynthetic electron-transfer chains. On the other hand, until recently, Rhodobacter sphaeroides was thought to have only one of these two cytochromes, the soluble Cyt c2Rs. Recent work indicated that this species has a gene, cycYRs, that is highly homologous to cycYRc, and in the work presented here, functional properties of its gene product (Cyt cyRs) are defined. It was found that Cyt cyRs is unable to participate in photosynthetic electron transfer, although it is active in respiratory electron transfer, unlike its R. capsulatus counterpart, Cyt cyRc. Chimeric constructs have shown that the photosynthetic incapability of Cyt cyRs is caused, at least in part, by its redox active subdomain, which carries the covalently bound heme. It, therefore, seems that this domain interacts differently with distinct redox partners, like the photochemical reaction center and the Cyt c oxidase, and allows the bacteria to funnel electrons efficiently to various destinations under different growth conditions. These findings raise an intriguing evolutionary issue in regard to cellular apoptosis: why do the mitochondria of higher organisms, unlike their bacterial ancestors, use only one soluble electron carrier in their respiratory electron-transport chains?
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