ArticlePlant physiology1999
Chloroplast-targeted ERD1 protein declines but its mRNA increases during senescence in Arabidopsis.
Article in Plant physiology, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed, 59 citations in OpenAlex.
- Protective Roles of Cytosolic and Plastidal Proteasomes on Abiotic Stress and Pathogen Invasion.Plants (Basel, Switzerland) · 2020Review
- PROTEIN PHOSPHATASE 2A-B'Plant physiology · 2020Article
- Visualization of Multicolored in vivo Organelle Markers for Co-Localization Studies in Oryza sativa.Molecules and cells · 2017Article
- Crystal structures reveal N-terminal Domain of Arabidopsis thaliana ClpD to be highly divergent from that of ClpC1.Scientific reports · 2017Article
- Both Hsp70 chaperone and Clp protease plastidial systems are required for protection against oxidative stress.Plant signaling & behavior · 2017Article
- Differential Regulation of Genes Coding for Organelle and Cytosolic ClpATPases under Biotic and Abiotic Stresses in Wheat.Frontiers in plant science · 2016Article
- Article
- Stromal protein degradation is incomplete in Arabidopsis thaliana autophagy mutants undergoing natural senescence.BMC research notes · 2013Article
- Insights into the Clp/HSP100 chaperone system from chloroplasts of Arabidopsis thaliana.The Journal of biological chemistry · 2011Article
- Genome-wide analysis of rice ClpB/HSP100, ClpC and ClpD genes.BMC genomics · 2010Article
- Article
- Inactivation of the clpC1 gene encoding a chloroplast Hsp100 molecular chaperone causes growth retardation, leaf chlorosis, lower photosynthetic activity, and a specific reduction in photosystem content.Plant physiology · 2004Article
- Classification of genes differentially expressed during water-deficit stress in Arabidopsis thaliana: an analysis using microarray and differential expression data.Annals of botany · 2002Article
- Plant mitochondria contain proteolytic and regulatory subunits of the ATP-dependent Clp protease.Plant molecular biology · 2001Article
- Plant proteolytic enzymes: possible roles during programmed cell death.Plant molecular biology · 2000Review
- Heat shock protein 101 plays a crucial role in thermotolerance in Arabidopsis.The Plant cell · 2000Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Arabidopsis ERD1 is a ClpC-like protein that sequence analysis suggests may interact with the chloroplast-localized ClpP protease to facilitate proteolysis. The mRNA encoded by the ERD1 gene has previously been shown to accumulate in response to senescence and to a variety of stresses and hormones. Here we show that the ERD1 protein, in contrast to the ERD1 mRNA, strongly declines in abundance with age, becoming undetectable in fully expanded leaves. Sequence analysis also suggests that ERD1 is chloroplast targeted, and we show in an in vitro system that the native protein is properly imported, processed, and present within the soluble fraction of the chloroplast, presumably the stroma. We show that ClpP protein, which is also present in the stroma, declines with age in parallel with ERD1. These results are consistent with the interaction of ERD1 and ClpP, but they suggest that it is unlikely that either plays a major role during senescence. Certain other chloroplast proteins decline with age coordinately with ERD1 and ClpP, suggesting that these declines are markers of an early age-mediated change that occurs within the chloroplast.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.