Evidence map›Paper›PMID 10194462›Full record

ReviewClinical microbiology reviews1999

Aspergillus fumigatus and aspergillosis.

J P Latgé

Open access · bronzeAbstract readReview
In one paragraph

Review in Clinical microbiology reviews, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 837 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
837citing papers in PubMed, 2 pooled it
34.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

837 citing papers in PubMed, 2 syntheses or guidelines pooled it, 2,283 citations in OpenAlex.

  1. Pooled it
  2. International journal of environmental research and public health · 2021
    Pooled it
  3. Trial
  4. Article
  5. Article
  6. Review
  7. Thermal adaptation crosstalk with azole response through lncRNA inbioRxiv : the preprint server for biology · 2026
    Article
  8. A Role for Non-Canonical Caspases in Fungal Allergic Airway Disease.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2026
    Article
  9. Review
  10. α-1,3-Glucan-Driven Remodeling of the Conidial Cell Wall in anJournal of the American Chemical Society · 2026
    Article
  11. Article
  12. Imaging of pediatric pulmonary infections: A pictorial review.World journal of clinical pediatrics · 2026
    Review
  13. Prevalence and Factors Associated WithOpen forum infectious diseases · 2026
    Article
  14. Global epidemiology of azole resistance inJAC-antimicrobial resistance · 2026
    Review
  15. Review
  16. Oxidoreductase geneMicrobiology spectrum · 2026
    Article
  17. Article
  18. Article
  19. Molecular mechanisms drivingFrontiers in molecular biosciences · 2026
    Review
  20. Article

777 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

J P LatgéLaboratoire des Aspergillus, Institut Pasteur, 75015 Paris, France. jplatge@pasteur.fr
Institut Pasteur · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aspergillus fumigatus is one of the most ubiquitous of the airborne saprophytic fungi. Humans and animals constantly inhale numerous conidia of this fungus. The conidia are normally eliminated in the immunocompetent host by innate immune mechanisms, and aspergilloma and allergic bronchopulmonary aspergillosis, uncommon clinical syndromes, are the only infections observed in such hosts. Thus, A. fumigatus was considered for years to be a weak pathogen. With increases in the number of immunosuppressed patients, however, there has been a dramatic increase in severe and usually fatal invasive aspergillosis, now the most common mold infection worldwide. In this review, the focus is on the biology of A. fumigatus and the diseases it causes. Included are discussions of (i) genomic and molecular characterization of the organism, (ii) clinical and laboratory methods available for the diagnosis of aspergillosis in immunocompetent and immunocompromised hosts, (iii) identification of host and fungal factors that play a role in the establishment of the fungus in vivo, and (iv) problems associated with antifungal therapy.

Indexed as

AnimalsAntigens, FungalAspergillosisAspergillus fumigatusDisease Models, AnimalHumansSerologic TestsVirulenceAntigens, Fungal

Identifiers

PMID10194462
PMCPMC88920
OpenAlexW2153911335

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.