ReviewClinical microbiology reviews1999
Molecular techniques for detection, species differentiation, and phylogenetic analysis of microsporidia.
Review in Clinical microbiology reviews, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
60 citing papers in PubMed, 260 citations in OpenAlex.
- Cross-kingdom noncoding RNA regulation facilitatesEngineering microbiology · 2026Article
- A New Host-Parasite Association: ALife (Basel, Switzerland) · 2026Article
- Characteristics and outcome of microsporidial keratitis.Journal of ophthalmic inflammation and infection · 2026Article
- Microscopic and Molecular Evaluation of Intestinal Microsporidia in Hemodialysis and Cancer Patients in Ilam Province.Journal of tropical medicine · 2026Article
- The in vitro potential of non-thermal atmospheric pressure plasma against Nosema ceranae infection in honeybees (Apis mellifera).Scientific reports · 2025Article
- First molecular detection and multilocus genotyping of Enterocytozoon bieneusi from pigs in Guangxi Zhuang Autonomous region, Southern China.BMC veterinary research · 2025Article
- Biological control of nosemosis in Apis mellifera L. with Acacia nilotica extract.Scientific reports · 2024Article
- Molecular detection and phylogenetic analysis of microsporidia in water and soil in Mosul city.Open veterinary journal · 2024Article
- First identification and coinfection detection of Enterocytozoon bieneusi, Encephalitozoon spp., Cryptosporidium spp. and Giardia duodenalis in diarrheic pigs in Southwest China.BMC microbiology · 2023Article
- Microsporidial keratoconjunctivitis - first outbreak in Japan.BMC infectious diseases · 2023Observational
- The microsporidian polar tube: origin, structure, composition, function, and application.Parasites & vectors · 2023Review
- Enterocytozoon bieneusi in fecal samples from calves and cows in Austria.Parasitology research · 2023Article
- The successful treatment ofFrontiers in cellular and infection microbiology · 2022Article
- The First Report on the Transovarial Transmission of MicrosporidianMicroorganisms · 2021Article
- Characterizing the Xenoma ofFrontiers in cellular and infection microbiology · 2021Article
- First identification and genotyping of Enterocytozoon bieneusi and Encephalitozoon spp. in pet rabbits in China.BMC veterinary research · 2020Article
- A Narrative Review of Microsporidial Infections of the Cornea.Ophthalmology and therapy · 2020Review
- Multilocus Sequence Typing and Population Genetic Analysis ofFrontiers in genetics · 2019Article
- Therapeutic targets for the treatment of microsporidiosis in humans.Expert opinion on therapeutic targets · 2018Review
- Case Report: Ocular Microsporidiosis: Case in a Patient Returning from India and Review of the Literature.The American journal of tropical medicine and hygiene · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microsporidia are obligate intracellular protozoan parasites that infect a broad range of vertebrates and invertebrates. These parasites are now recognized as one of the most common pathogens in human immunodeficiency virus-infected patients. For most patients with infectious diseases, microbiological isolation and identification techniques offer the most rapid and specific determination of the etiologic agent. This is not a suitable procedure for microsporidia, which are obligate intracellular parasites requiring cell culture systems for growth. Therefore, the diagnosis of microsporidiosis currently depends on morphological demonstration of the organisms themselves. Although the diagnosis of microsporidiosis and identification of microsporidia by light microscopy have greatly improved during the last few years, species differentiation by these techniques is usually impossible and transmission electron microscopy may be necessary. Immunfluorescent-staining techniques have been developed for species differentiation of microsporidia, but the antibodies used in these procedures are available only at research laboratories at present. During the last 10 years, the detection of infectious disease agents has begun to include the use of nucleic acid-based technologies. Diagnosis of infection caused by parasitic organisms is the last field of clinical microbiology to incorporate these techniques and molecular techniques (e.g., PCR and hybridization assays) have recently been developed for the detection, species differentiation, and phylogenetic analysis of microsporidia. In this paper we review human microsporidial infections and describe and discuss these newly developed molecular techniques.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.