ArticleGenetics1999
Suppressor analysis of the Saccharomyces cerevisiae gene REC104 reveals a genetic interaction with REC102.
Article in Genetics, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Meiosis in budding yeast.Genetics · 2023Article
- Computed structures of core eukaryotic protein complexes.Science (New York, N.Y.) · 2021Article
- Advances Towards How Meiotic Recombination Is Initiated: A Comparative View and Perspectives for Plant Meiosis Research.International journal of molecular sciences · 2019Review
- Functional interactions among members of the meiotic initiation complex in fission yeast.Current genetics · 2010Article
- Tethering recombination initiation proteins in Saccharomyces cerevisiae promotes double strand break formation.Genetics · 2009Article
- Spo11 and the Formation of DNA Double-Strand Breaks in Meiosis.Genome dynamics and stability · 2008Article
- Interactions between Mei4, Rec114, and other proteins required for meiotic DNA double-strand break formation in Saccharomyces cerevisiae.Chromosoma · 2007Article
- Both conserved and non-conserved regions of Spo11 are essential for meiotic recombination initiation in yeast.Molecular genetics and genomics : MGG · 2006Article
- Saccharomyces cerevisiae Mer2, Mei4 and Rec114 form a complex required for meiotic double-strand break formation.Genetics · 2006Article
- The signal from the initiation of meiotic recombination to the first division of meiosis.Eukaryotic cell · 2004Article
- Spatial organization and dynamics of the association of Rec102 and Rec104 with meiotic chromosomes.The EMBO journal · 2004Article
- Support for a meiotic recombination initiation complex: interactions among Rec102p, Rec104p, and Spo11p.Molecular and cellular biology · 2003Article
- Functional interactions between SPO11 and REC102 during initiation of meiotic recombination in Saccharomyces cerevisiae.Genetics · 2002Article
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Authors and funding
3 authors.
Funding
Abstract
REC104 is a gene required for the initiation of meiotic recombination in Saccharomyces cerevisiae. To better understand the role of REC104 in meiosis, we used an in vitro mutagenesis technique to create a set of temperature-conditional mutations in REC104 and used one ts allele (rec104-8) in a screen for high-copy suppressors. An increased dosage of the early exchange gene REC102 was found to suppress the conditional recombinational reduction in rec104-8 as well as in several other conditional rec104 alleles. However, no suppression was observed for a null allele of REC104, indicating that the suppression by REC102 is not "bypass" suppression. Overexpression of the early meiotic genes REC114, RAD50, HOP1, and RED1 fails to suppress any of the rec104 conditional alleles, indicating that the suppression might be specific to REC102.
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Registered trials
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