ArticleBritish journal of cancer1999
Mutation analysis of the Fanconi anaemia A gene in breast tumours with loss of heterozygosity at 16q24.3.
Article in British journal of cancer, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 18 citations in OpenAlex.
- A rare FANCA gene variation as a breast cancer susceptibility allele in an Iranian population.Molecular medicine reports · 2017Article
- A comprehensive study of chromosome 16q in invasive ductal and lobular breast carcinoma using array CGH.Oncogene · 2006Article
- A novel duplication polymorphism in the FANCA promoter and its association with breast and ovarian cancer.BMC cancer · 2005Article
- Expression analysis of candidate breast tumour suppressor genes on chromosome 16q.Breast cancer research : BCR · 2005Article
- Visibility of the environmental noise modulating population dynamics.Proceedings. Biological sciences · 2000Article
Corrections and comments
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Authors and funding
11 authors at 5 institutions in 4 countries.
Funding
Abstract
The recently identified Fanconi anaemia A (FAA) gene is located on chromosomal band 16q24.3 within a region that has been frequently reported to show loss of heterozygosity (LOH) in breast cancer. FAA mutation analysis of 19 breast tumours with specific LOH at 16q24.3 was performed. Single-stranded conformational polymorphism (SSCP) analysis on cDNA and genomic DNA, and Southern blotting failed to identify any tumour-specific mutations. Five polymorphisms were identified, but frequencies of occurrence did not deviate from those in a normal control population. Therefore, the FAA gene is not the gene targeted by LOH at 16q24.3 in breast cancer. Another tumour suppressor gene in this chromosomal region remains to be identified.
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