Evidence map›Paper›PMID 10097917›Full record

ArticleDiabetes care1999

Impaired fasting glucose or impaired glucose tolerance. What best predicts future diabetes in Mauritius?

J E Shaw, P Z Zimmet, M de Courten, G K Dowse, P Chitson, H Gareeboo, F Hemraj, D Fareed, J Tuomilehto, K G Alberti

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Diabetes care, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02621060 (Effect of the Administration of Chlorogenic Acid on Glucemic Control, Insulin Secretion and Insulin Sensitivity in Patients With Impaired Glucose Tolerance), which is not on this map. Cited by 84 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
84citing papers in PubMed, 5 pooled it
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02621060 phase2completednot on this mapstarted 2015, after this paper: background citation

Effect of the Administration of Chlorogenic Acid on Glucemic Control, Insulin Secretion and Insulin Sensitivity in Patients With Impaired Glucose Tolerance

TypeinterventionalSponsorUniversity of GuadalajaraRan2015 to 2016Enrolled30ConditionsImpaired Glucose ToleranceArmsPlacebo, Chlorogenic acid
3 · Its place in the literature

Who cites it

84 citing papers in PubMed, 5 syntheses or guidelines pooled it, 330 citations in OpenAlex.

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24 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 3 countries.

J E ShawInternational Diabetes Institute, Melbourne, Australia. jshaw@idi.org.au
P Z Zimmet
M de Courten
G K Dowse
P Chitson
H Gareeboo
F Hemraj
D Fareed
J Tuomilehto
K G Alberti
Baker Heart and Diabetes Institute · AUMinistry of Health and Quality of Life · MU

Funding

DIABETES IN PACIFIC - GENETIC ENVIRONMENTAL INTERACTIONSR01DK025446 · NIDDK · INTERNATIONAL DIABETES INSTITUTE · PI ZIMMET, PAUL Z · 1986 to 1999
–
NIDDK NIH HHS DK-25446
6 · The paper itself

Abstract

objectiveTo determine if impaired fasting glucose (IFG; fasting plasma glucose level 6.1-6.9 mmol/l) can predict future type 2 diabetes as accurately as does impaired glucose tolerance (IGT; 2-h plasma glucose level 7.8-11.0 mmol/l). RESEARCH DESIGN AND

methodsA longitudinal population-based study was performed with surveys in 1987 and 1992 on the island of Mauritius, assessing diabetes status by the oral glucose tolerance test. A total of 3,717 subjects took part in both surveys. Of these subjects, 3,229 were not diabetic in 1987 and formed the basis of this study.

resultsAt baseline, there were 607 subjects with IGT and 266 subjects with IFG. There were 297 subjects who developed diabetes by 1992. For predicting progression to type 2 diabetes, the sensitivity, specificity, and positive predictive values were 26, 94, and 29% for IFG and 50, 84, and 24% for IGT, respectively. Only 26% of subjects that progressed to type 2 diabetes were predicted by their IFG values, but a further 35% could be identified by also considering IGT. The sensitivities were 24% for IFG and 37% for IGT in men and 26% for IFG and 66% for IGT in women, respectively.

conclusionsThese data demonstrate the higher sensitivity of IGT over IFG for predicting progression to type 2 diabetes. Screening by the criteria for IFG alone would identify fewer people who subsequently progress to type 2 diabetes than would the oral glucose tolerance test.

Indexed as

AdultAgedBlood GlucoseDiabetes Mellitus, Type 2Disease ProgressionFastingFemaleForecastingGlucose IntoleranceGlucose Tolerance TestHealth SurveysHumansIncidenceLongitudinal StudiesMaleMauritiusBlood Glucose

Identifiers

PMID10097917
OpenAlexW2076921335

What OpenQuestion holds

Texttitle and abstract
measurements read10
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.