ArticleNature biotechnology1999
Keeping the biotechnology of antisense in context.
Article in Nature biotechnology, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed.
- Frameworks for transformational breakthroughs in RNA-based medicines.Nature reviews. Drug discovery · 2024Review
- Silencing of Thrips palmi UHRF1BP1 and PFAS Using Antisense Oligos Induces Mortality and Reduces Tospovirus Titer in Its VectorPathogens (Basel, Switzerland) · 2022Article
- AMD Genomics: Non-Coding RNAs as Biomarkers and Therapeutic Targets.Journal of clinical medicine · 2022Review
- Reexamining assumptions about miRNA-guided gene silencing.Nucleic acids research · 2022Review
- Guidelines for Experiments Using Antisense Oligonucleotides and Double-Stranded RNAs.Nucleic acid therapeutics · 2019Article
- Chemistry, mechanism and clinical status of antisense oligonucleotides and duplex RNAs.Nucleic acids research · 2018Review
- Non-coding RNAs as drug targets.Nature reviews. Drug discovery · 2017Review
- Antitumor effects of EGFR antisense guanidine-based peptide nucleic acids in cancer models.ACS chemical biology · 2013Article
- siRNAs target sites selection of ezrin and the influence of RNA interference on ezrin expression and biological characters of osteosarcoma cells.Molecular and cellular biochemistry · 2012Article
- Ezrin mRNA target site selection for DNAzymes using secondary structure and hybridization thermodynamics.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2011Article
- Radiolabeled oligonucleotides for antisense imaging.Current organic synthesis · 2011Article
- Effect of Steric Constraint at the γ-Backbone Position on the Conformations and Hybridization Properties of PNAs.Journal of nucleic acids · 2011Article
- Crystal structure of chiral gammaPNA with complementary DNA strand: insights into the stability and specificity of recognition and conformational preorganization.Journal of the American Chemical Society · 2010Article
- Synthesis of conformationally preorganized and cell-permeable guanidine-based gamma-peptide nucleic acids (gammaGPNAs).The Journal of organic chemistry · 2009Article
- Review
- Synthesis, thermal stability and resistance to enzymatic hydrolysis of the oligonucleotides containing 5-(N-aminohexyl)carbamoyl-2'-O-methyluridines.Nucleic acids research · 2003Article
- Artificial neural network prediction of antisense oligodeoxynucleotide activity.Nucleic acids research · 2002Article
- Nuclear antisense effects of neutral, anionic and cationic oligonucleotide analogs.Nucleic acids research · 2001Article
- Statistical prediction of single-stranded regions in RNA secondary structure and application to predicting effective antisense target sites and beyond.Nucleic acids research · 2001Article
- Mapping of RNA accessible sites by extension of random oligonucleotide libraries with reverse transcriptase.RNA (New York, N.Y.) · 2001Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
10096271What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.