ReviewMutation research1999
Are adaptive mutations due to a decline in mismatch repair? The evidence is lacking.
Review in Mutation research, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 35 citations in OpenAlex.
- Article
- Hfq links translation repression to stress-induced mutagenesis inGenes & development · 2017Article
- Determinants of spontaneous mutation in the bacterium Escherichia coli as revealed by whole-genome sequencing.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Stress-Induced Mutagenesis.EcoSal Plus · 2012Article
- Stress responses and genetic variation in bacteria.Mutation research · 2005Review
- Adaptive point mutation and adaptive amplification pathways in the Escherichia coli Lac system: stress responses producing genetic change.Journal of bacteriology · 2004Article
- Role of Escherichia coli DNA polymerase IV in in vivo replication fidelity.Journal of bacteriology · 2004Article
- Involvement of error-prone DNA polymerase IV in stationary-phase mutagenesis in Pseudomonas putida.Journal of bacteriology · 2004Article
- General stress response regulator RpoS in adaptive mutation and amplification in Escherichia coli.Genetics · 2004Article
- Different spectra of stationary-phase mutations in early-arising versus late-arising mutants of Pseudomonas putida: involvement of the DNA repair enzyme MutY and the stationary-phase sigma factor RpoS.Journal of bacteriology · 2002Article
- Saturation of DNA mismatch repair and error catastrophe by a base analogue in Escherichia coli.Genetics · 2002Article
- Article
- Adaptive mutation: implications for evolution.BioEssays : news and reviews in molecular, cellular and developmental biology · 2000Review
- Antagonism of ultraviolet-light mutagenesis by the methyl-directed mismatch-repair system of Escherichia coli.Genetics · 2000Article
- Adaptive mutation in Escherichia coli.Cold Spring Harbor symposia on quantitative biology · 2000Review
- Mechanisms of mutation in nondividing cells. Insights from the study of adaptive mutation in Escherichia coli.Annals of the New York Academy of Sciences · 1999Review
- Mechanisms of stationary phase mutation: a decade of adaptive mutation.Annual review of genetics · 1999Review
- Stress-induced mutagenesis in bacteria.Critical reviews in biochemistry and molecular biologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
The levels of proteins required for methyl-directed mismatch repair appear to decline in stationary-phase and nutritionally-deprived cells of Escherichia coli. It has been hypothesized that error-correction by the system also declines, and this decline is responsible for adaptive or stationary-phase mutations. However, evidence in support of this hypothesis is lacking. The mismatch repair system is no less effective in correcting errors during prolonged selection than it is during growth. Furthermore, mismatch repair proteins supplied in excess reduce both growth-dependent and adaptive mutation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.