ArticleJournal of bacteriology1999
Mutational analysis of the vacA promoter provides insight into gene transcription in Helicobacter pylori.
Article in Journal of bacteriology, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Vacuolating Cytotoxin A (VacA) and Extracellular Vesicles inIranian journal of pathology · 2025Review
- There Are No Insurmountable Barriers: Passage of theMembranes · 2023Review
- Helicobacter pylori vacA transcription is genetically-determined and stratifies the level of human gastric inflammation and atrophy.Journal of clinical pathology · 2016Article
- Review
- Expression of the Helicobacter pylori virulence factor vacuolating cytotoxin A (vacA) is influenced by a potential stem-loop structure in the 5' untranslated region of the transcript.Molecular microbiology · 2015Article
- Analysis of Helicobacter pylori cagA promoter elements required for salt-induced upregulation of CagA expression.Infection and immunity · 2012Article
- Genotypic and phenotypic variation of Lewis antigen expression in geographically diverse Helicobacter pylori isolates.Helicobacter · 2011Article
- Analysis of cagA in Helicobacter pylori strains from Colombian populations with contrasting gastric cancer risk reveals a biomarker for disease severity.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2011Article
- Article
- The HP0165-HP0166 two-component system (ArsRS) regulates acid-induced expression of HP1186 alpha-carbonic anhydrase in Helicobacter pylori by activating the pH-dependent promoter.Journal of bacteriology · 2007Article
- Detection of prokaryotic promoters from the genomic distribution of hexanucleotide pairs.BMC bioinformatics · 2006Article
- Type V protein secretion pathway: the autotransporter story.Microbiology and molecular biology reviews : MMBR · 2004Review
- Growth phase-dependent regulation of target gene promoters for binding of the essential orphan response regulator HP1043 of Helicobacter pylori.Journal of bacteriology · 2002Article
- Genome-wide transcriptional profiling in a histidine kinase mutant of Helicobacter pylori identifies members of a regulon.Journal of bacteriology · 2002Article
- Analysis of DNA regulatory elements required for expression of the Legionella pneumophila icm and dot virulence genes.Journal of bacteriology · 2002Article
- Promoters of the CATG-specific methyltransferase gene hpyIM differ between iceA1 and iceA2 Helicobacter pylori strains.Journal of bacteriology · 2001Article
- Differential gene expression from two transcriptional units in the cag pathogenicity island of Helicobacter pylori.Infection and immunity · 2001Article
- Essential thioredoxin-dependent peroxiredoxin system from Helicobacter pylori: genetic and kinetic characterization.Journal of bacteriology · 2001Article
- Systematic identification of selective essential genes in Helicobacter pylori by genome prioritization and allelic replacement mutagenesis.Journal of bacteriology · 2001Article
- Transcriptional analysis of major heat shock genes of Helicobacter pylori.Journal of bacteriology · 2000Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Analysis of 12 Helicobacter pylori promoters indicates the existence of a consensus -10 hexamer (TAtaaT) but little conservation of -35 sequences. In this study, mutations in either the H. pylori vacA -10 region or the -35 region resulted in decreased vacA transcription and suggested that an extended -10 motif is utilized. Thus, despite the lack of a -35 consensus sequence for H. pylori promoters, the -35 region plays a functional role in vacA transcription.
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