ArticleThorax1999
Morbidity from asthma in relation to regular treatment: a community based study.
Article in Thorax, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- School-based self-management interventions for asthma in children and adolescents: a mixed methods systematic review.The Cochrane database of systematic reviews · 2019Pooled it
- Inhaled corticosteroids effects on bone in asthmatic and COPD patients: a quantitative systematic review.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2003Pooled it
- Poor adherence with inhaled corticosteroids for asthma: can using a single inhaler containing budesonide and formoterol help?The British journal of general practice : the journal of the Royal College of General Practitioners · 2008Trial
- Efficacy of low and high dose inhaled corticosteroid in smokers versus non-smokers with mild asthma.Thorax · 2005Trial
- Self-management of asthma in general practice, asthma control and quality of life: a randomised controlled trial.Thorax · 2003Trial
- Trial
- Treating severe paediatric asthma with mepolizumab or omalizumab: a protocol for the TREAT randomised non-inferiority trial.BMJ open · 2024Article
- Treating the Side Effects of Exogenous Glucocorticoids; Can We Separate the Good From the Bad?Endocrine reviews · 2023Review
- Using routinely collected primary care records to identify and investigate severe asthma: a scoping review.NPJ primary care respiratory medicine · 2021Article
- Severe bronchial asthma in children: a review of novel biomarkers used as predictors of the disease.Journal of asthma and allergy · 2018Review
- Review
- Prescribing for osteoporosis following the use of inhaled and oral glucocorticoids in general practice.British journal of clinical pharmacology · 2004Article
- Funhaler spacer: improving adherence without compromising delivery.Archives of disease in childhood · 2003Article
- Review
- Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe extent to which asthma morbidity in the community occurs in patients who are having relatively little treatment or in those on step 3 or above of the British asthma management guidelines is uncertain. We have looked at this in a community population in southern Nottinghamshire.
methodsA cross sectional review of treatment in all patients over the age of four with diagnosed asthma was carried out in five large general practices (population 38 865) in 1995/6 using computerised general practice records. The patients' usual treatment was obtained from prescription data and categorised by the appropriate step on the British guidelines on asthma management. Two measures of morbidity, the request for 10 or more short acting beta agonist inhalers a year or the need for a course of oral corticosteroids in the last year, were related to the regular treatment of the patients.
resultsOf the 3373 patients (8. 7%) given a diagnosis of asthma, the percentage on steps 1, 2, 3, 4, and 5 of treatment were 54%, 22%, 11%, 3.6%, and 1%, respectively, with a further 8% having had no treatment. During the past year 13. 6% had been prescribed 10 or more beta agonist inhalers and 12.5% had received at least one course of oral corticosteroids. Both measures occurred more frequently in patients taking more prophylactic treatment (step 3 or above). Nevertheless, because most patients were on steps 1 and 2 of the treatment guidelines, more than half the patients requiring high doses of inhaled beta agonists or a course of oral prednisolone came from those taking low dose or no regular inhaled corticosteroid.
conclusionsEvidence of morbidity from asthma was found in many patients taking little or no prophylactic medication and this should be amenable to improved education. A different approach may be needed for patients with continuing morbidity who are already taking higher doses of prophylactic medication.
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