ArticleProceedings of the National Academy of Sciences of the United States of America1999
CORE-SINEs: eukaryotic short interspersed retroposing elements with common sequence motifs.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.
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Who cites it
59 citing papers in PubMed.
- Rewiring of SINE-MIR enhancer topology and Esrrb modulation in expanded and naive pluripotency.Genome biology · 2025Article
- Identification and Characterization of LINE and SINE Retrotransposons in the African Hedgehog (Genes · 2025Article
- Widespread HCD-tRNA derived SINEs in bivalves rely on multiple LINE partners and accumulate in genic regions.Mobile DNA · 2024Article
- The Role of Transposable Elements of the Human Genome in Neuronal Function and Pathology.International journal of molecular sciences · 2022Review
- Identification and functional characterization of the German cockroach, Blattella germanica, short interspersed nuclear elements.PloS one · 2022Article
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- Diversity of short interspersed nuclear elements (SINEs) in lepidopteran insects and evidence of horizontal SINE transfer between baculovirus and lepidopteran hosts.BMC genomics · 2021Article
- Identification and characterization of repetitive DNA in the genus Didelphis Linnaeus, 1758 (Didelphimorphia, Didelphidae) and the use of satellite DNAs as phylogenetic markers.Genetics and molecular biology · 2021Article
- Article
- Article
- Retrotransposons spread potential cis-regulatory elements during mammary gland evolution.Nucleic acids research · 2019Article
- Riding the Wave: The SINE-Specific V Highly-Conserved Domain Spread into Mammalian Genomes Exploiting the Replication Burst of the MER6 DNA Transposon.International journal of molecular sciences · 2019Article
- Evolution of an X-Linked miRNA Family Predominantly Expressed in Mammalian Male Germ Cells.Molecular biology and evolution · 2019Article
- LINEs Contribute to the Origins of Middle Bodies of SINEs besides 3' Tails.Genome biology and evolution · 2018Article
- Evolution of Two Short Interspersed Elements in Callorhinchus milii (Chondrichthyes, Holocephali) and Related Elements in Sharks and the Coelacanth.Genome biology and evolution · 2017Article
- Whole-genome expression analysis of mammalian-wide interspersed repeat elements in human cell lines.DNA research : an international journal for rapid publication of reports on genes and genomes · 2017Article
- Viral tRNA Mimicry from a Biocommunicative Perspective.Frontiers in microbiology · 2017Review
- Rare horizontal transmission does not hide long-term inheritance of SINE highly conserved domains in the metazoan evolution.Current zoology · 2016Article
- RUDI, a short interspersed element of the V-SINE superfamily widespread in molluscan genomes.Molecular genetics and genomics : MGG · 2016Article
- MetaSINEs: Broad Distribution of a Novel SINE Superfamily in Animals.Genome biology and evolution · 2016Article
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2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A 65-bp "core" sequence is dispersed in hundreds of thousands copies in the human genome. This sequence was found to constitute the central segment of a group of short interspersed elements (SINEs), referred to as mammalian-wide interspersed repeats, that proliferated before the radiation of placental mammals. Here, we propose that the core identifies an ancient tRNA-like SINE element, which survived in different lineages such as mammals, reptiles, birds, and fish, as well as mollusks, presumably for >550 million years. This element gave rise to a number of sequence families (CORE-SINEs), including mammalian-wide interspersed repeats, whose distinct 3' ends are shared with different families of long interspersed elements (LINEs). The evolutionary success of the generic CORE-SINE element can be related to the recruitment of the internal promoter from highly transcribed host RNA as well as to its capacity to adapt to changing retropositional opportunities by sequence exchange with actively amplifying LINEs. It reinforces the notion that the very existence of SINEs depends on the cohabitation with both LINEs and the host genome.
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