ArticleGenome research1999
Analysis of 148 kb of genomic DNA around the wnt1 locus of Fugu rubripes.
Article in Genome research, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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Who cites it
13 citing papers in PubMed, 43 citations in OpenAlex.
- Analysis of the wnt1 regulatory chromosomal landscape.Development genes and evolution · 2019Article
- Expression of Wnt gene family and frizzled receptors in head and neck squamous cell carcinomas.Virchows Archiv : an international journal of pathology · 2009Article
- Expression profiling and comparative genomics identify a conserved regulatory region controlling midline expression in the zebrafish embryo.Genome research · 2004Article
- v-Src induces Shc binding to tyrosine 63 in the cytoplasmic domain of the LDL receptor-related protein 1.Oncogene · 2003Article
- Comparative analysis of vertebrate dystrophin loci indicate intron gigantism as a common feature.Genome research · 2003Article
- Transcriptional regulation of the stem cell leukemia gene (SCL)--comparative analysis of five vertebrate SCL loci.Genome research · 2002Article
- Comparative analysis of the ETV6 gene in vertebrate genomes from pufferfish to human.Oncogene · 2001Article
- Mapping of complex regulatory elements by pufferfish/zebrafish transgenesis.Proceedings of the National Academy of Sciences of the United States of America · 2001Article
- Ancient genome duplications did not structure the human Hox-bearing chromosomes.Genome research · 2001Article
- A cell cycle-dependent protein serves as a template-specific translation initiation factor.Genes & development · 2000Article
- Genomic sequence analysis of Fugu rubripes CFTR and flanking genes in a 60 kb region conserving synteny with 800 kb of human chromosome 7.Genome research · 2000Article
- Estimation of synteny conservation and genome compaction between pufferfish (Fugu) and human.Yeast (Chichester, England) · 2000Article
- Generation and analysis of 25 Mb of genomic DNA from the pufferfish Fugu rubripes by sequence scanning.Genome research · 1999Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The analysis of the sequence of approximately 150 kb of a genomic region corresponding to the wnt1 gene of the Japanese pufferfish Fugu rubripes confirms the compact structure of the genome. Fifteen genes were found in this region, and 26.6% of the analyzed sequence is coding sequence. With an average intergenic distance of <5 kb, this gene density is comparable to that of Caenorhabditis elegans. The compactness of this region corresponds to the reduction of the overall size of the genome, consistent with the conclusion that the gene number in Fugu and human genomes is approximately the same. Eight of the genes have been mapped in the human genome and all of them are found in the chromosomal band 12q13, indicating a high degree of synteny in both species, Fugu and human. Comparative sequence analysis allows us to identify potential regulatory elements for wnt1 and ARF3, which are common to fish and mammals.
Indexed as
Identifiers
10077531PMC310722W1809977585What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.