Evidence map›Paper›PMID 10074557›Full record

ArticleJournal of clinical microbiology1999

Isolation of a human rotavirus strain with a super-short RNA pattern and a new P2 subtype.

T Nakagomi, Y Horie, Y Koshimura, H B Greenberg, O Nakagomi

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Journal of clinical microbiology, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

T NakagomiDepartment of Microbiology, Akita University School of Medicine, Hondo, Akita 010-8543, Japan. nakagom@ipc.akita-u.ac.jp
Y Horie
Y Koshimura
H B Greenberg
O Nakagomi
Akita University · JPUnited States Department of Veterans Affairs · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Super-short rotavirus strains that have a rearranged gene segment 11 are rarely found in humans, and only five isolates, all from Southeast Asia, have been described in the literature. We report the first isolation in Japan from an infant with severe diarrhea of a rotavirus possessing a super-short RNA pattern. This strain, designated AU19, had a G1 VP7 and is also the first isolate in Japan that possesses a P2[6] VP4. Furthermore, the P2[6] VP4 carried by AU19 was divergent in the hypervariable region of the amino acid sequence from the P2A[6] VP4s carried by asymptomatic neonatal strains or from the P2B[6] VP4 carried by porcine rotavirus strain Gottfried. Thus, AU19 is likely to represent a new VP4 subtype, which we propose to call P2C. Given the recent emergence of the P2[6] VP4s in India, Brazil, and the United States and the role of VP4 in protective immunity, further scrutiny is justified to see whether the emergence of the previously underrepresented P2[6] VP4 serotype is related to this new P2 subtype.

Indexed as

Capsid ProteinsBase SequenceCapsidDiarrheaDNA PrimersGene RearrangementGenes, ViralHumansInfantJapanMolecular Sequence DataPhylogenyRNA, ViralRotavirusRotavirus InfectionsSerotypingCapsid ProteinsDNA PrimersRNA, ViralVP4 protein, Rotavirus

Identifiers

PMID10074557
PMCPMC88680
OpenAlexW2142573614

What OpenQuestion holds

Texttitle and abstract
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.