ArticleJournal of clinical microbiology1999
Development and characterization of complex DNA fingerprinting probes for the infectious yeast Candida dubliniensis.
Article in Journal of clinical microbiology, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed, 76 citations in OpenAlex.
- Genetic diversity and relatedness of Candida albicans isolates from humans and animals in Iran: implications for infection control.GMS hygiene and infection control · 2026Article
- Exploring the Biology, Virulence, and General Aspects ofInfection and drug resistance · 2024Review
- Article
- Comparison of Switching and Biofilm Formation between MTL-Homozygous Strains of Candida albicans and Candida dubliniensis.Eukaryotic cell · 2015Article
- Candida dubliniensis: epidemiology and phenotypic methods for identification.Mycopathologia · 2010Review
- Longitudinal genotyping of Candida dubliniensis isolates reveals strain maintenance, microevolution, and the emergence of itraconazole resistance.Journal of clinical microbiology · 2010Article
- Erythematous oral candidiasis in patients with controlled type II diabetes mellitus and complete dentures.Mycopathologia · 2010Article
- A Ser29Leu substitution in the cytosine deaminase Fca1p is responsible for clade-specific flucytosine resistance in Candida dubliniensis.Antimicrobial agents and chemotherapy · 2009Article
- Extensive chromosome rearrangements distinguish the karyotype of the hypovirulent species Candida dubliniensis from the virulent Candida albicans.Fungal genetics and biology : FG & B · 2008Article
- Multilocus sequence typing reveals that the population structure of Candida dubliniensis is significantly less divergent than that of Candida albicans.Journal of clinical microbiology · 2008Article
- Use of fluconazole as a surrogate marker to predict susceptibility and resistance to voriconazole among 13,338 clinical isolates of Candida spp. Tested by clinical and laboratory standards institute-recommended broth microdilution methods.Journal of clinical microbiology · 2007Article
- Development and evaluation of a rapid latex agglutination test using a monoclonal antibody to identify Candida dubliniensis colonies.Journal of clinical microbiology · 2006Article
- Novel 5-flucytosine-resistant clade of Candida dubliniensis from Saudi Arabia and Egypt identified by Cd25 fingerprinting.Journal of clinical microbiology · 2005Article
- Reduced azole susceptibility in genotype 3 Candida dubliniensis isolates associated with increased CdCDR1 and CdCDR2 expression.Antimicrobial agents and chemotherapy · 2005Article
- Evaluation of a rapid immunochromatographic assay for identification of Candida albicans and Candida dubliniensis.Journal of clinical microbiology · 2004Article
- The closely related species Candida albicans and Candida dubliniensis can mate.Eukaryotic cell · 2004Article
- Cross-resistance between fluconazole and ravuconazole and the use of fluconazole as a surrogate marker to predict susceptibility and resistance to ravuconazole among 12,796 clinical isolates of Candida spp.Journal of clinical microbiology · 2004Article
- Release of a potent polymorphonuclear leukocyte chemoattractant is regulated by white-opaque switching in Candida albicans.Infection and immunity · 2004Article
- Molecular mechanisms of itraconazole resistance in Candida dubliniensis.Antimicrobial agents and chemotherapy · 2003Article
- Racial distribution of Candida dubliniensis colonization among South Africans.Journal of clinical microbiology · 2003Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Using a strategy to clone large genomic sequences containing repetitive elements from the infectious yeast Candida dubliniensis, the three unrelated sequences Cd1, Cd24, and Cd25, with respective molecular sizes of 15,500, 10,000, and 16,000 bp, were cloned and analyzed for their efficacy as DNA fingerprinting probes. Each generated a complex Southern blot hybridization pattern with endonuclease-digested genomic DNA. Cd1 generated an extremely variable pattern that contained all of the bands of the pattern generated by the repeat element RPS of Candida albicans. We demonstrated that Cd1 does not contain RPS but does contain a repeat element associated with RPS throughout the C. dubliniensis genome. The Cd1 pattern was the least stable over time both in vitro and in vivo and for that reason proved most effective in assessing microevolution. Cd24, which did not exhibit microevolution in vitro, was highly variable in vivo, suggesting in vivo-dependent microevolution. Cd25 was deemed the best probe for broad epidemiological studies, since it was the most stable over time, was the only truly C. dubliniensis-specific probe of the three, generated the most complex pattern, was distributed throughout all C. dubliniensis chromosomes, and separated a worldwide collection of 57 C. dubliniensis isolates into two distinct groups. The presence of a species-specific repetitive element in Cd25 adds weight to the already substantial evidence that C. dubliniensis represents a bona fide species.
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