ArticleJournal of bacteriology1999
Functional identification of the product of the Bacillus subtilis yvaL gene as a SecG homologue.
Article in Journal of bacteriology, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 46 citations in OpenAlex.
- Protein trafficking across the cell envelope of gram-positive bacteria.Journal of bacteriology · 2025Review
- Relative contributions of non-essential Sec pathway components and cell envelope-associated proteases to high-level enzyme secretion by Bacillus subtilis.Microbial cell factories · 2020Article
- The Cellular Mechanisms that Ensure an Efficient Secretion in Streptomyces.Antibiotics (Basel, Switzerland) · 2018Review
- Synthetic effects of secG and secY2 mutations on exoproteome biogenesis in Staphylococcus aureus.Journal of bacteriology · 2010Article
- Protein transport across and into cell membranes in bacteria and archaea.Cellular and molecular life sciences : CMLS · 2010Review
- Towards the development of Bacillus subtilis as a cell factory for membrane proteins and protein complexes.Microbial cell factories · 2008Article
- The SsrA-SmpB ribosome rescue system is important for growth of Bacillus subtilis at low and high temperatures.Journal of bacteriology · 2007Article
- Two additional components of the accessory sec system mediating export of the Streptococcus gordonii platelet-binding protein GspB.Journal of bacteriology · 2005Article
- FlhF, the third signal recognition particle-GTPase of Bacillus subtilis, is dispensable for protein secretion.Journal of bacteriology · 2004Article
- Quantitation of the capacity of the secretion apparatus and requirement for PrsA in growth and secretion of alpha-amylase in Bacillus subtilis.Journal of bacteriology · 2001Article
- Signal peptide-dependent protein transport in Bacillus subtilis: a genome-based survey of the secretome.Microbiology and molecular biology reviews : MMBR · 2000Review
- Re-annotating the Mycoplasma pneumoniae genome sequence: adding value, function and reading frames.Nucleic acids research · 2000Article
- SecYEG assembles into a tetramer to form the active protein translocation channel.The EMBO journal · 2000Article
- Preprotein translocation by a hybrid translocase composed of Escherichia coli and Bacillus subtilis subunits.Journal of bacteriology · 1999Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Protein export in Escherichia coli is mediated by translocase, a multisubunit membrane protein complex with SecA as the peripheral subunit and the SecY, SecE, and SecG proteins as the integral membrane domain. In the gram-positive bacterium Bacillus subtilis, SecA, SecY, and SecE have been identified through genetic analysis. Sequence comparison of the Bacillus chromosome identified a potential homologue of SecG, termed YvaL. A chromosomal disruption of the yvaL gene results in mild cold sensitivity and causes a beta-lactamase secretion defect. The cold sensitivity is exacerbated by overexpression of the secretory protein alpha-amylase, whereas growth and beta-lactamase secretion are restored by coexpression of yvaL or the E. coli secG gene. These results indicate that the yvaL gene codes for a protein that is functionally homologous to SecG.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.