ArticleGenetics1999
Major histocompatibility complex differentiation in Sacramento River chinook salmon.
Article in Genetics, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- Evaluating the Potential Fitness Effects of Chinook Salmon (Animals : an open access journal from MDPI · 2023Article
- Comparative Susceptibilities of Selected California Chinook Salmon and Steelhead Populations to Isolates of L Genogroup Infectious Hematopoietic Necrosis Virus (IHNV).Animals : an open access journal from MDPI · 2022Article
- MHC polymorphism and disease resistance to Vibrio anguillarum in 8 families of half-smooth tongue sole (Cynoglossus semilaevis).BMC genetics · 2011Article
- Sexual conflict inhibits female mate choice for major histocompatibility complex dissimilarity in Chinook salmon.Proceedings. Biological sciences · 2010Article
- PCA-correlated SNPs for structure identification in worldwide human populations.PLoS genetics · 2007Article
- Patterns of historical balancing selection on the salmonid major histocompatibility complex class II beta gene.Journal of molecular evolution · 2007Article
- Patterns of variability at the major histocompatibility class II alpha locus in Atlantic salmon contrast with those at the class I locus.Immunogenetics · 2005Article
- Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The chinook salmon of the Sacramento River, California, have been reduced to a fraction of their former abundance because of human impact and use of the river system. Here we examine the genetic variation at a major histocompatibility complex class II exon in the four Sacramento chinook salmon runs. Examination of the alleles found in these and other chinook salmon revealed nucleotide patterns consistent with selection for amino acid replacement at the putative antigen-binding sites. We found a significant amount of variation in each of the runs, including the federally endangered winter run. All of the samples were in Hardy-Weinberg proportions. A significant amount of genetic differentiation between runs was revealed by several measures of differentiation. Winter run was the most genetically divergent, while the spring, late-fall, and fall runs were less differentiated.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.