ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences1998
Predicting insecticide resistance: mutagenesis, selection and response.
Review in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Insecticidal and immunotoxic actions of 2-octenoic acid in the green bottle fly Lucilia sericata (Diptera: Calliphoridae).Medical and veterinary entomology · 2026Article
- A proof-of-concept experimental-theoretical model to predict pesticide resistance evolution.Heredity · 2025Article
- The Evolution of Pesticide Resistance: A Data-Driven Case Study of Chlorantraniliprole Resistance inEvolutionary applications · 2025Review
- Utility and challenges of using whole-genome resequencing to detect emerging insect and mite resistance in agroecosystems.Evolutionary applications · 2022Review
- Standing genetic variation in laboratory populations of insecticide-susceptibleEvolutionary applications · 2021Article
- The evolutionary origins of pesticide resistance.Biological reviews of the Cambridge Philosophical Society · 2019Article
- The Wiggle Index: An Open Source Bioassay to Assess Sub-Lethal Insecticide Response in Drosophila melanogaster.PloS one · 2015Article
- Article
- The importance of modelling the spread of insecticide resistance in a heterogeneous environment: the example of adding synergists to bed nets.Malaria journal · 2012Article
- Genetic erosion impedes adaptive responses to stressful environments.Evolutionary applications · 2012Article
- Genome-wide association studies reveal a simple genetic basis of resistance to naturally coevolving viruses in Drosophila melanogaster.PLoS genetics · 2012Article
- Scientific standards and the regulation of genetically modified insects.PLoS neglected tropical diseases · 2012Article
- The ovicidal, larvacidal and adulticidal properties of 5,5'-dimethyl-2,2'-bipyridyl against Drosophila melanogaster.PloS one · 2012Article
- Insecticide resistance mechanisms in the green peach aphid Myzus persicae (Hemiptera: Aphididae) I: A transcriptomic survey.PloS one · 2012Article
- Rapid experimental evolution of pesticide resistance in C. elegans entails no costs and affects the mating system.PloS one · 2008Article
- Genetic analysis and cross-resistance spectrum of a laboratory-selected chlorfenapyr resistant strain of two-spotted spider mite (Acari: Tetranychidae).Experimental & applied acarology · 2004Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Strategies to manage resistance to a particular insecticide have usually been devised after resistance has evolved. If it were possible to predict likely resistance mechanisms to novel insecticides before they evolved in the field, it might be feasible to have programmes that manage susceptibility. With this approach in mind, single-gene variants of the Australian sheep blowfly, Lucilia cuprina, resistant to dieldrin, diazinon and malathion, were selected in the laboratory after mutagenesis of susceptible strains. The genetic and molecular bases of resistance in these variants were identical to those that had previously evolved in natural populations. Given this predictive capacity for known resistances, the approach was extended to anticipate possible mechanisms of resistance to cyromazine, an insecticide to which L. cuprina populations remain susceptible after almost 20 years of exposure. Analysis of the laboratory-generated resistant variants provides an explanation for this observation. The variants show low levels of resistance and a selective advantage over susceptibles for only a limited concentration range. These results are discussed in the context of the choice of insecticides for control purposes and of delivery strategies to minimize the evolution of resistance.
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